Canagliflozin belongs to which drug class?

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Study for the Foundation Year Pharmacy – Clinical Practice Test. Prepare with detailed questions, step-by-step explanations, and test format insights. Enhance your readiness and confidence!

Multiple Choice

Canagliflozin belongs to which drug class?

Explanation:
Canagliflozin belongs to the SGLT2 inhibitor class. Its action is to block the sodium-glucose cotransporter 2 in the proximal tubule of the kidney, which normally reabsorbs most of the filtered glucose. By inhibiting this transporter, more glucose is excreted in the urine, lowering blood glucose levels. This renal mechanism distinguishes it from other antidiabetic drug classes: GLP-1 receptor agonists enhance insulin secretion via incretin signaling; DPP-4 inhibitors raise incretin levels by preventing their breakdown; ACE inhibitors act on the renin-angiotensin system to lower blood pressure. So, the best description of canagliflozin’s class is SGLT2 inhibitor.

Canagliflozin belongs to the SGLT2 inhibitor class. Its action is to block the sodium-glucose cotransporter 2 in the proximal tubule of the kidney, which normally reabsorbs most of the filtered glucose. By inhibiting this transporter, more glucose is excreted in the urine, lowering blood glucose levels. This renal mechanism distinguishes it from other antidiabetic drug classes: GLP-1 receptor agonists enhance insulin secretion via incretin signaling; DPP-4 inhibitors raise incretin levels by preventing their breakdown; ACE inhibitors act on the renin-angiotensin system to lower blood pressure. So, the best description of canagliflozin’s class is SGLT2 inhibitor.

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