In the HFpEF patient described, which of the following current medications is a diuretic?

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Multiple Choice

In the HFpEF patient described, which of the following current medications is a diuretic?

Explanation:
The main concept is identifying a drug that increases urine output to remove excess fluid, i.e., a diuretic. In heart failure with preserved ejection fraction (HFpEF), managing congestion is key, so diuretics are used to relieve edema and reduce preload. Furosemide is a loop diuretic. It works by blocking the Na+/K+/2Cl− transporter in the thick ascending limb of the loop of Henle, causing excretion of sodium, chloride, and water. This diuretic effect lowers fluid buildup and alleviates symptoms like edema and breathlessness. Ramipril is an ACE inhibitor that lowers blood pressure and afterload, helping with heart remodeling but does not directly promote diuresis. Amlodipine is a calcium channel blocker that reduces vascular resistance; it is not a diuretic. Metformin is an antidiabetic medication with no diuretic action. So, the medication that is a diuretic is furosemide.

The main concept is identifying a drug that increases urine output to remove excess fluid, i.e., a diuretic. In heart failure with preserved ejection fraction (HFpEF), managing congestion is key, so diuretics are used to relieve edema and reduce preload.

Furosemide is a loop diuretic. It works by blocking the Na+/K+/2Cl− transporter in the thick ascending limb of the loop of Henle, causing excretion of sodium, chloride, and water. This diuretic effect lowers fluid buildup and alleviates symptoms like edema and breathlessness.

Ramipril is an ACE inhibitor that lowers blood pressure and afterload, helping with heart remodeling but does not directly promote diuresis. Amlodipine is a calcium channel blocker that reduces vascular resistance; it is not a diuretic. Metformin is an antidiabetic medication with no diuretic action.

So, the medication that is a diuretic is furosemide.

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