Tiotropium belongs to which drug class?

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Study for the Foundation Year Pharmacy – Clinical Practice Test. Prepare with detailed questions, step-by-step explanations, and test format insights. Enhance your readiness and confidence!

Multiple Choice

Tiotropium belongs to which drug class?

Explanation:
Tiotropium is a long-acting muscarinic antagonist. It works by blocking acetylcholine at muscarinic receptors in the airways, especially M3 receptors on smooth muscle, which prevents bronchoconstriction and produces sustained bronchodilation for about a day. This makes it a maintenance bronchodilator used in COPD (and sometimes in difficult asthma). It’s not a beta-agonist, so it doesn’t stimulate adrenergic receptors to open airways; it’s not an inhaled corticosteroid, which reduces inflammation rather than directly relaxing airway smooth muscle; and it’s not a leukotriene receptor antagonist, which blocks inflammatory mediators rather than cholinergic-induced bronchoconstriction.

Tiotropium is a long-acting muscarinic antagonist. It works by blocking acetylcholine at muscarinic receptors in the airways, especially M3 receptors on smooth muscle, which prevents bronchoconstriction and produces sustained bronchodilation for about a day. This makes it a maintenance bronchodilator used in COPD (and sometimes in difficult asthma). It’s not a beta-agonist, so it doesn’t stimulate adrenergic receptors to open airways; it’s not an inhaled corticosteroid, which reduces inflammation rather than directly relaxing airway smooth muscle; and it’s not a leukotriene receptor antagonist, which blocks inflammatory mediators rather than cholinergic-induced bronchoconstriction.

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