Tiotropium is which class of inhaled medication?

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Study for the Foundation Year Pharmacy – Clinical Practice Test. Prepare with detailed questions, step-by-step explanations, and test format insights. Enhance your readiness and confidence!

Multiple Choice

Tiotropium is which class of inhaled medication?

Explanation:
Tiotropium is a long-acting muscarinic antagonist (LAMA). It works by blocking muscarinic receptors, mainly M3, in the airway smooth muscle, which prevents acetylcholine from triggering bronchoconstriction and mucus production. This leads to sustained bronchodilation lasting about a day, so it’s used as a maintenance inhaled medication. This mechanism is distinct from a long-acting beta-2 agonist (which relaxes smooth muscle via beta-2 receptor stimulation and cAMP), an inhaled corticosteroid (which reduces airway inflammation through gene regulation), or a PDE4 inhibitor (which raises cAMP by preventing its breakdown and is typically not inhaled).

Tiotropium is a long-acting muscarinic antagonist (LAMA). It works by blocking muscarinic receptors, mainly M3, in the airway smooth muscle, which prevents acetylcholine from triggering bronchoconstriction and mucus production. This leads to sustained bronchodilation lasting about a day, so it’s used as a maintenance inhaled medication. This mechanism is distinct from a long-acting beta-2 agonist (which relaxes smooth muscle via beta-2 receptor stimulation and cAMP), an inhaled corticosteroid (which reduces airway inflammation through gene regulation), or a PDE4 inhibitor (which raises cAMP by preventing its breakdown and is typically not inhaled).

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