What is the correct dosing for Mebeverine in irritable bowel syndrome?

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Study for the Foundation Year Pharmacy – Clinical Practice Test. Prepare with detailed questions, step-by-step explanations, and test format insights. Enhance your readiness and confidence!

Multiple Choice

What is the correct dosing for Mebeverine in irritable bowel syndrome?

Explanation:
Mebeverine is used to relieve IBS symptoms by relaxing smooth muscle in the gut, and the standard regimen is a 135 mg tablet taken three times a day, usually before meals. This provides a total daily dose of 405 mg and aligns with the pattern of symptoms that often occur around meals, giving coverage throughout the day. Dosing once daily would likely leave symptoms uncontrolled for much of the day, while twice daily or four times daily dosing with a nonstandard strength does not match common prescribing information. Therefore, the best schedule is 135 mg tablets taken three times daily.

Mebeverine is used to relieve IBS symptoms by relaxing smooth muscle in the gut, and the standard regimen is a 135 mg tablet taken three times a day, usually before meals. This provides a total daily dose of 405 mg and aligns with the pattern of symptoms that often occur around meals, giving coverage throughout the day. Dosing once daily would likely leave symptoms uncontrolled for much of the day, while twice daily or four times daily dosing with a nonstandard strength does not match common prescribing information. Therefore, the best schedule is 135 mg tablets taken three times daily.

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