Which food is commonly avoided in people with G6PD deficiency due to the risk of hemolysis?

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Multiple Choice

Which food is commonly avoided in people with G6PD deficiency due to the risk of hemolysis?

Explanation:
In G6PD deficiency, red blood cells can’t generate enough NADPH to keep glutathione in its reduced form, so they can’t effectively neutralize oxidative stress. When a strong oxidant is present, the hemoglobin and cell membranes are damaged, leading to hemolysis. Fava beans contain compounds (vicine and convicine) that trigger oxidative stress in red blood cells. In people with G6PD deficiency, this oxidative challenge can precipitate a rapid, sometimes severe, hemolytic episode known as favism. Spinach, carrots, and rice do not pose the same oxidative threat and are generally considered safe for most individuals with G6PD deficiency.

In G6PD deficiency, red blood cells can’t generate enough NADPH to keep glutathione in its reduced form, so they can’t effectively neutralize oxidative stress. When a strong oxidant is present, the hemoglobin and cell membranes are damaged, leading to hemolysis.

Fava beans contain compounds (vicine and convicine) that trigger oxidative stress in red blood cells. In people with G6PD deficiency, this oxidative challenge can precipitate a rapid, sometimes severe, hemolytic episode known as favism.

Spinach, carrots, and rice do not pose the same oxidative threat and are generally considered safe for most individuals with G6PD deficiency.

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