Which of the following is not a symptom of phenytoin overdose?

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Study for the Foundation Year Pharmacy – Clinical Practice Test. Prepare with detailed questions, step-by-step explanations, and test format insights. Enhance your readiness and confidence!

Multiple Choice

Which of the following is not a symptom of phenytoin overdose?

Explanation:
Phenytoin overdose mainly causes central nervous system depression and cerebellar signs. Signs like nystagmus and ataxia reflect disruption of coordination and eye movements due to CNS toxicity, while sedation shows overall depressant effect on brain activity. These are classic features of phenytoin overdose. Hypoglycaemia, on the other hand, is not a typical manifestation of phenytoin toxicity; low blood glucose presents with symptoms such as sweating, tremor, tachycardia, and confusion, not with nystagmus or ataxia. So the option that does not fit as a phenytoin overdose symptom is hypoglycaemia.

Phenytoin overdose mainly causes central nervous system depression and cerebellar signs. Signs like nystagmus and ataxia reflect disruption of coordination and eye movements due to CNS toxicity, while sedation shows overall depressant effect on brain activity. These are classic features of phenytoin overdose. Hypoglycaemia, on the other hand, is not a typical manifestation of phenytoin toxicity; low blood glucose presents with symptoms such as sweating, tremor, tachycardia, and confusion, not with nystagmus or ataxia. So the option that does not fit as a phenytoin overdose symptom is hypoglycaemia.

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