Which of the following medicines is a non-sedating antihistamine?

Study for the Foundation Year Pharmacy – Clinical Practice Test. Prepare with detailed questions, step-by-step explanations, and test format insights. Enhance your readiness and confidence!

Multiple Choice

Which of the following medicines is a non-sedating antihistamine?

Explanation:
Non-sedating antihistamines block H1 receptors to relieve allergy symptoms while minimizing drowsiness because they poorly cross the blood-brain barrier and have less central nervous system impact. Fexofenadine is a classic example of a second-generation antihistamine with this property, offering relief from sneezing, itching, and runny nose without noticeable sedation. The other medicines listed are not antihistamines: levothyroxine is a thyroid hormone, atorvastatin is a statin, and amlodipine is a calcium channel blocker—none of which target histamine receptors to provide allergy relief.

Non-sedating antihistamines block H1 receptors to relieve allergy symptoms while minimizing drowsiness because they poorly cross the blood-brain barrier and have less central nervous system impact. Fexofenadine is a classic example of a second-generation antihistamine with this property, offering relief from sneezing, itching, and runny nose without noticeable sedation. The other medicines listed are not antihistamines: levothyroxine is a thyroid hormone, atorvastatin is a statin, and amlodipine is a calcium channel blocker—none of which target histamine receptors to provide allergy relief.

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