Which over-the-counter medication is most appropriate for rapid relief of outdoor-triggered allergic rhinitis symptoms in an adult?

• A. Cetirizine 10 mg tablet
• B. Diphenhydramine 25 mg tablet
• C. Loratadine 10 mg tablet
• D. Fexofenadine 180 mg tablet

Answer: (A)

Rapid relief of outdoor-triggered allergic rhinitis relies on how quickly an antihistamine starts working. Diphenhydramine, while fast-acting, is a first‑generation antihistamine with notable drowsiness and cognitive side effects, making it less ideal for daytime outdoor use. Among the other options, cetirizine tends to produce relief relatively quickly and has much less sedating effect than it, while loratadine and fexofenadine have slower onset. For an adult needing prompt symptom relief with fewer daytime side effects, cetirizine is the best choice. If congestion is prominent, adding an intranasal product could help, but the question targets rapid relief of symptoms like sneezing and runny nose.